Use G53 in same line with motion code to execute motion in machine coordinates.
G53 is a G-code used to move a machine to a specific absolute machine coordinate, bypassing the current coordinate system and any offsets that may be in effect. It is used to move the machine to a specific point in the machine's coordinate system, regardless of the current position or any offsets that have been applied.
The G53 command is usually followed by one or more axis words, such as X, Y, and Z, to specify the position the machine should move to. For example, G53 X10 Y5 Z0 would move the X, Y, and Z axes to the position (10,5,0) in the machine's coordinate system.
G53
Move to machine position X100, Y50.
G53 G00 X100 Y50